Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bicistronic Vector for the Creation of Stable Mammalian Cell Lines that Predisposes All Antibiotic-Resistant Cells to Express Recombinant Protein

1 Jan 1996

Abstract excerpt

We have developed an improved vector for the stable expression of recombinant protein in mammalian cells. In this vector, designated pCIN, both the recombinant cDNA and the neomycin phosphotransferase selection marker are transcribed from a single promoter element. To facilitate translation of the second open reading frame, the encephalomyocarditis virus internal ribosome entry site has been inserted into the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Viral Infections and Immunology Research
Share to Viral Infectious Diseases and Gene Expression in Insects
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8770413
DOI: 10.2144/96201st05

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bicistronic Vector for the Creation of Stable Mammalian Cell Lines that Predisposes All Antibiotic-Resistant Cells to Express Recombinant ProteinPMID 8770413Read ↗

Comparison of seven different heterologous protein expression systems for the production of the serotonin transporter.Semantic proximity Read ↗

Improved vectors for stable expression of foreign genes in mammalian cells by use of the untranslated leader sequence from EMC virusSemantic proximity Read ↗

High-Level Production of Recombinant Proteins in CHO Cells Using a Dicistronic DHFR Intron Expression VectorSemantic proximity Read ↗

Rapid selection of transgenic mammalian cells via diphtheria toxin resistanceSemantic proximity Read ↗

Genetic and Functional Dissection of the Role of Individual 5-HT2 Receptors as Entry Receptors for JC PolyomavirusSemantic proximity Read ↗

Human serotonin 5-HT7 receptor: cloning and pharmacological characterisation of two receptor variants.Semantic proximity Read ↗

A human cell-surface receptor for xenotropic and polytropic murine leukemia viruses: Possible role in G protein-coupled signal transductionSemantic proximity Read ↗

The recombinant 5-HT1A receptor: G protein coupling and signalling pathways.Semantic proximity Read ↗

The human serotonin 5-HT2C receptor: complete cDNA, genomic structure, and alternatively spliced variant.Semantic proximity Read ↗

The Human Polyomavirus, JCV, Uses Serotonin Receptors to Infect CellsSemantic proximity Read ↗

Novel brain-specific 5-HT4 receptor splice variants show marked constitutive activity: role of the C-terminal intracellular domain.Semantic proximity Read ↗

Structure-guided selection of puromycin N-acetyltransferase mutants with enhanced selection stringency for deriving mammalian cell lines expressing recombinant proteins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.