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Article

Cloning of a Human Homolog of theDrosophila Minibrain/Rat Dyrk Gene from “the Down Syndrome Critical Region” of Chromosome 21

1 Aug 1996

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 8769099
DOI: 10.1006/bbrc.1996.1135

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Click a neighbor to travelStep 1 · 12 closest

Cloning of a Human Homolog of theDrosophila Minibrain/Rat Dyrk Gene from “the Down Syndrome Critical Region” of Chromosome 21PMID 8769099Read ↗

Isolation of human and murine homologues of the Drosophila minibrain gene: human homologue maps to 21q22.2 in the Down syndrome "critical region".Semantic proximity Read ↗

Human minibrain homologue (MNBH/DYRK1): characterization, alternative splicing, differential tissue expression, and overexpression in Down syndrome.Semantic proximity Read ↗

Dyrk1a from Gene Function in Development and Physiology to Dosage Correction across Life Span in Down SyndromeSemantic proximity Read ↗

A human homologue of Drosophila minibrain (MNB) is expressed in the neuronal regions affected in Down syndrome and maps to the critical regionSemantic proximity Read ↗

Neuronal overexpression of <i>DYRK1A/minibrain</i> alters motor decline, neurodegeneration and synaptic plasticity in <i>Drosophila</i>Semantic proximity Read ↗

Characterization of Caenorhabditis elegans Homologs of the Down Syndrome Candidate Gene DYRK1ASemantic proximity Read ↗

Systematic Functional Characterization of Human 21st Chromosome Orthologs in <i>Caenorhabditis elegans</i>Semantic proximity Read ↗

DYRK1A (Dual-Specificity Tyrosine-Phosphorylated and -Regulated Kinase 1A): A Gene with Dosage Effect During Development and NeurogenesisSemantic proximity Read ↗

Clinical manifestations of the deletion of Down syndrome critical region including DYRK1A and KCNJ6.Semantic proximity Read ↗

New Perspectives of Dyrk1A Role in Neurogenesis and Neuropathologic Features of Down SyndromeSemantic proximity Read ↗

Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome.Semantic proximity Read ↗

Truncation of the Down syndrome candidate gene DYRK1A in two unrelated patients with microcephaly.Semantic proximity Read ↗

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