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Article

An IgG‐transporting Fc receptor expressed in the syncytiotrophoblast of human placenta

1 Jul 1996

Abstract excerpt

During normal human pregnancy, maternal IgG crosses the placenta and provides passive immunity for the fetus. In so doing, IgG passes through two cellular barriers: the syncytiotrophoblast and the fetal capillary endothelium. The Fc region of IgG is required for its transport across the placenta, but the Fc receptors responsible have not been identified definitively. We recently reported the isolation from a...

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Identifiers

PMID: 8766556
DOI: 10.1002/eji.1830260718

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