Article
SOS-inducing ability of native and mutant microbial ribonucleases.
Mutation research - 22 Jul 1996
Ilinskaya O N, Karamova N S, Ivanchenko O B, Kipenskaya L V
Abstract excerpt
The results of genotoxicity testing of microbial ribonucleases from Bacillus species with different catalytic activity obtained by site-directed mutagenesis in SOS chromotest are reported. At the concentrations 0.1-1 mg/ml, the induction factor for wild-type bacillar binase, barnase and mutant Arg58Lys binase with 100% activity was found to be significantly higher than 1.5 (1.8-2.8). Mutant RNases having...
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