Article
Prevention of DNA damage in spores and in vitro by small, acid-soluble proteins from Bacillus species.
Journal of bacteriology - 1 Mar 1993
Fairhead H, Setlow B, Setlow P
Abstract excerpt
The DNA in dormant spores of Bacillus species is saturated with a group of nonspecific DNA-binding proteins, termed alpha/beta-type small, acid-soluble spore proteins (SASP). These proteins alter DNA structure in vivo and in vitro, providing spore resistance to UV light. In addition, heat treatments (e.g., 85 degrees C for 30 min) which give little killing of wild-type spores of B. subtilis kill > 99% of spores...
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