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Article

In vitro genotoxicity tests for polyhydroxybutyrate--a synthetic biomaterial.

Toxicology in vitro : an international journal published in association with BIBRA - 1 Feb 2008

Ali Abdulaziz Qaid, Kannan Thirumulu Ponnuraj, Ahmad Azlina, Samsudin Ab Rani

Abstract excerpt

The aims of this study are to determine the mutagenicity of a locally produced polyhydroxybutyrate (PHB) using Salmonella mutagenicity test and to find out if PHB altered the expression of p53 and c-myc proto-oncogenes and bcl-xl and bcl-xs anti-apoptotic genes in the human fibroblast cell line, MRC-5. Different concentrations of PHB were incubated with special genotypic variants of Salmonella strains (TA1535,...

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Identifiers

PMID: 17892925
DOI: 10.1016/j.tiv.2007.08.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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