Article
Soluble beta-amyloid induces Alzheimer's disease features in human fibroblasts and in neuronal tissues.
Life sciences - 1 Jan 1996
Etcheberrigaray R, Payne J L, Alkon D L
Abstract excerpt
It has been shown that K+ channels, Cp20 (a 20kD GTP-binding protein), and intracellular calcium release, play a key role in associative memory storage. These same elements have been shown to be altered in fibroblasts from Alzheimer's Disease (AD) patients. In addition, it has been shown that PKC...
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