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Article

A locus for Fanconi anemia on 16q determined by homozygosity mapping.

American journal of human genetics - 1 Aug 1996

Gschwend M, Levran O, Kruglyak L, Ranade K, Verlander P C, Shen S, Faure S, Weissenbach J, Altay C, Lander E S, Auerbach A D, Botstein D

Abstract excerpt

We report the results of a genomewide scan using homozygosity mapping to identify genes causing Fanconi anemia, a genetically heterogeneous recessive disorder. By studying 23 inbred families, we detected linkage to a locus causing Fanconi anemia near marker D16S520 (16q24.3). Although -65% of our families displayed clear linkage to D16S520, we found strong evidence (P = .0013) of genetic heterogeneity. This...

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Identifiers

PMID: 8755924
PMCID: PMC1914713

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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