Article
A PCR-based genetic linkage map of human chromosome 16.
Genomics - 1 Jul 1994
Shen Y, Kozman H M, Thompson A, Phillips H A, Holman K, Nancarrow J, Lane S, Chen L Z, Apostolou S, Doggett N A
Abstract excerpt
A high-resolution cytogenetic-based physical map and a genetic linkage map of human chromosome 16 have been developed based on 79 PCR-typable genetic markers and 2 Southern-based RFLP markers. The PCR-based markers were previously characterized polymorphic (AC)n repeats. Two approaches have led to the characterization of 47 highly informative genetic markers spread along chromosome 16, some of which are closely...
Topics
- Animals
- Base Sequence
- Chromosome Mapping
- Chromosomes, Human, Pair 16
- DNA
- Female
- Genetic Linkage
- Genetic Markers
- Genotype
- Humans
- Hybrid Cells
- Male