Article
A PCR-based genetic linkage map of human chromosome 16.
Genomics - 1 Jul 1994
Shen Y, Kozman H M, Thompson A, Phillips H A, Holman K, Nancarrow J, Lane S, Chen L Z, Apostolou S, Doggett N A
Abstract excerpt
A high-resolution cytogenetic-based physical map and a genetic linkage map of human chromosome 16 have been developed based on 79 PCR-typable genetic markers and 2 Southern-based RFLP markers. The PCR-based markers were previously characterized polymorphic (AC)n repeats. Two approaches have led to the characterization of 47 highly informative genetic markers spread along chromosome 16, some of which are closely...
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