Article
[Polymorphic variability of apolipoprotein B genes and insulin receptor in essential hypertension].
Polskie Archiwum Medycyny Wewnetrznej - 1 Mar 1996
Pisarska M
Abstract excerpt
The association of the polymorphisms of two candidate genes with essential hypertension was studied in 74 hypertensive and 118 normotensive subjects. Two restrictions endonucleases were used: PstI for the insulin receptor gene and PvuII for the apolipoprotein B gene. PstI RFLP in the INSR gene locus consists of two polymorphic alleles P1 (1800bp) and P2 (1500bp). Frequencies of these alleles in general population...
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