Article
The associations between G972R polymorphism of the IRS-1 gene, insulin resistance, salt sensitivity and non-dipper hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Oct 2011
Dziwura Joanna, Bińczak-Kuleta Agnieszka, Miazgowski Tomasz, Ziemak Joanna, Widecka Krystyna
Abstract excerpt
The aim of this study was to assess the association between G972R polymorphism of the insulin receptor substrate-1 (IRS-1) gene and the circadian variation in blood pressure, insulin sensitivity and salt sensitivity in subjects with uncomplicated, never-treated essential hypertension receiving low-, normal- and high-salt diets. The study was performed on 115 subjects aged 27.48±5.1 years with never-treated,...
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