Article
[Q192R polymorphism of PON-1 gene in type 2 diabetic patients].
TSitologiia i genetika - 1 Jan 2000
Gorshunskaia M Iu, Karachentsev Iu I, Atramentova L A, Tyzhnenko T V, Kravchun N A, Pocherniaev A K, Poltorak V V
Abstract excerpt
Polymorphism of PON-1 gene in 192 position of amino acid sequence of enzyme paraoxonase 1 was studied. For this research we have used the blood samples of 96 patients with T2DM and 123 healthy habitants of Kharkiv. Frequencies of alleles for the patients (pQ = 0,65, pR = 0,35) and the healthies (PQ = 0,70 and pR = 0,30) did not differentiate meaningfully. Distribution of the genotypes for healthy people does not...
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