Article
Independent, marked associations of alleles of the insulin receptor and dipeptidyl carboxypeptidase-I genes with essential hypertension.
Clinical science (London, England : 1979) - 1 Aug 1993
Morris B J, Zee R Y, Ying L H, Griffiths L R
Abstract excerpt
1. There is evidence to suggest that essential hypertension is a polygenic disorder and that it arises from yet-to-be-identified predisposing variants of certain genes that influence blood pressure. The cloning of various hormone, enzyme, adrenoceptor and hormone receptor genes whose products are...
Topics
- Adult
- Alleles
- Cross-Sectional Studies
- Genes
- Humans
- Hypertension
- Middle Aged
- Peptidyl-Dipeptidase A
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
- Receptor, Insulin