Association of a RFLP for the insulin receptor gene, but not insulin, with essential hypertension.

doi:10.1016/s0006-291x(05)81445-7

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Article

Association of a RFLP for the insulin receptor gene, but not insulin, with essential hypertension.

Biochemical and biophysical research communications - 27 Nov 1991

Ying L H, Zee R Y, Griffiths L R, Morris B J

Abstract excerpt

Insulin has cardiovascular actions and patients with essential hypertension display insulin resistance. A cross-sectional study of the R1 RFLP of the insulin receptor gene (INSR) was carried out in 67 hypertensive (HT) and 75 normotensive (NT) subjects whose parents had a similar blood pressure status at age greater than or equal to 50. The frequency of the minor (+) allele was 0.31 in HTs and 0.44 in NTs, and...

Topics

Adult
Aged
Alleles
Blood Pressure
Chromosome Mapping
Chromosomes, Human, Pair 19
DNA
DNA Probes
Deoxyribonucleases, Type II Site-Specific
Gene Frequency
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Hypertension

Insulin

Leukocytes

Polymorphism, Restriction Fragment Length

Receptor, Insulin

Reference Values

Source

Open in PubMed

Identifiers

PMID: 1683535
DOI: 10.1016/s0006-291x(05)81445-7

Genes

INSR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1683535-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Association of a RFLP for the insulin receptor gene, but not insulin, with essential hypertension.PMID 1683535Read ↗

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