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Excess amino acid polymorphism in mitochondrial DNA: contrasts among genes from Drosophila, mice, and humans.

Molecular biology and evolution - 1 Jul 1996

Rand D M, Kann L M

Abstract excerpt

Recent studies of mitochondrial DNA (mtDNA) variation in mammals and Drosophila have shown an excess of amino acid variation within species (replacement polymorphism) relative to the number of silent and replacement differences fixed between species. To examine further this pattern of nonneutral mtDNA evolution, we present sequence data for the ND3 and ND5 genes from 59 lines of Drosophila melanogaster and 29...

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PMID: 8754210
DOI: 10.1093/oxfordjournals.molbev.a025634

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