Article
Racial comparison of p53 alterations in breast cancer: difference in prognostic value.
In vivo (Athens, Greece) - 1 Jan 2000
Shiao Y H, Chen V W, Wu X C, Scheer W D, Lehmann H P, Malcom G T, Boudreau D A, Ruiz B, Correa P
Abstract excerpt
A significant difference in breast cancer survival between blacks and whites has been observed in the United States. Biological variation between races has been suggested to explain the difference. We investigated the difference by comparing the prognostic value of p53 alterations (mutations and protein accumulation) between black and white breast cancer patients. Black, but not white, patients with p53 mutations...
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