Article
HLA*A2 confers mortality risk for cardiovascular disease in Pimans.
Tissue antigens - 1 Mar 1996
Williams R C, Hanson R L, Pettitt D J, Sievers M L, Nelson R G, Knowler W C
Abstract excerpt
A sample of 1465 full heritage Piman Indians from Arizona were typed for the serological antigens of the HLA class I loci and then incorporated into a survival study that ended December 31, 1991. The total follow-up time was 11,749 person-years with an average of 8.0 years per person. During the study 298 persons died, 54 from cardiovascular disease (CVD). Allele HLA*A2 conferred a 4.94 fold rate for death from...
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