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Article

Blood concentration of pantoprazole sodium is significantly high in hepatogenic peptic ulcer patients, especially those with a poor CYP2C19 metabolism.

Journal of digestive diseases - 1 Feb 2009

Shao Jian Guo, Jiang Wen, Li Ke Qing, Lu Jian Rong, Sun Yuan Yuan

Abstract excerpt

OBJECTIVE: To determine the plasma concentration of pantoprazole sodium by high performance liquid chromatography and its distribution in patients with different CYP2C19 genotypes in an attempt to provide experimental data for the clinical dosage adjustment of the drug. METHODS: Patients with liver disease and associated peptic ulcer were genotyped according to their CYP2C19 wild-type sequences and mutations in...

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Identifiers

PMID: 19236548
DOI: 10.1111/j.1751-2980.2008.00363.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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