Article
Aromatic interactions define the binding of the alphavirus spike to its nucleocapsid.
Structure (London, England : 1993) - 15 May 1996
Skoging U, Vihinen M, Nilsson L, Liljeström P
Abstract excerpt
BACKGROUND: Most enveloped viruses bud from infected cells by a process in which viral intracellular core components interact with cytoplasmic domains of transmembrane spike glycoproteins. We have demonstrated previously that a tyrosine motif in the cytoplasmic domain of the Semliki Forest virus (SFV) spike glycoprotein E2 is absolutely essential for budding. In contrast, hardly anything is known regarding which...
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