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Article

Role of mitochondrial DNA tRNA leucine and glucagon receptor missense mutations in Utah white diabetic patients.

Diabetes care - 1 May 1996

Elbein S C, Hoffman M D

Abstract excerpt

Recently, subtypes of typical NIDDM were suggested based on missense mutations of mitochondrial DNA [tRNALeu(UUR)] and the glucagon receptor gene (Gly40Ser). Together these mutations might explain NIDDM in 5--8% of patients. To test the hypothesis that these mutations play an important role in a Northern European population with a strong family history of diabetes, we screened members of 45 families selected for...

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Identifiers

PMID: 8732719
DOI: 10.2337/diacare.19.5.507

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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