Article
APOE alleles in Alzheimer's disease and vascular dementia in a population aged 85+.
Neurobiology of aging - 1 Jan 2000
Sulkava R, Kainulainen K, Verkkoniemi A, Niinistö L, Sobel E, Davanipour Z, Polvikoski T, Haltia M, Kontula K
Abstract excerpt
Apolipoprotein E genotyping was carried out in a stratified random sample of 52 patients with Alzheimer's disease, 48 patients with vascular or mixed dementia, and 49 nondemented controls in a population-based study of people aged 85 and older (the Vantaa 85+ Study). Our results indicate that the apolipoprotein E epsilon 4 allele is associated with approximately a twofold increase in clinically diagnosed...
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