Article
Characteristics of single- and double-stranded RNA synthesis by a rotavirus SA-11 mutant thermosensitive in the RNA polymerase gene.
Intervirology - 1 Jan 1995
Munoz M, Rios M, Spencer E
Abstract excerpt
The phenotype of a rotavirus SA-11 mutant, ts C, which carries a mutation in the gene coding for the viral RNA polymerase was studied in vitro. ts C viral transcription proved to be sensitive to temperature in a different way to that previously described. Like the wild type, the ts C mutant has a...
Topics
- Animals
- DNA-Directed RNA Polymerases
- Deoxyadenine Nucleotides
- Electrophoresis, Polyacrylamide Gel
- Hot Temperature
- Macaca mulatta
- Mutation
- RNA
- RNA, Double-Stranded
- RNA, Viral
- Rotavirus
- Transcription, Genetic
- Vidarabine Phosphate