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Article

BRCA1 mutations in African Americans.

Human genetics - 1 Jan 2000

Panguluri R C, Brody L C, Modali R, Utley K, Adams-Campbell L, Day A A, Whitfield-Broome C, Dunston G M

Abstract excerpt

The breast cancer predisposing gene, BRCA1, was analyzed for germline mutations in 45 African American families at high-risk for hereditary breast cancer. Patients were considered high-risk if they had a family history of the disease, early onset breast cancer, bilateral breast cancer, or breast and ovarian cancer. The entire BRCA1 coding and flanking intron regions have been examined by single stranded...

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Source

Identifiers

PMID: 10480351
DOI: 10.1007/s004399900085

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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