Article
The human glycine receptor beta subunit: primary structure, functional characterisation and chromosomal localisation of the human and murine genes.
Brain research. Molecular brain research - 1 Jan 1996
Handford C A, Lynch J W, Baker E, Webb G C, Ford J H, Sutherland G R, Schofield P R
Abstract excerpt
The inhibitory glycine receptor (GlyR) is a pentameric receptor comprised of alpha and beta subunits, of which the beta subunit has not been characterised in humans. A 2106 bp cDNA, isolated from a human hippocampal cDNA library, contained an open reading frame of 497 amino acids which encodes the beta subunit of the human GlyR. The mature human GlyR beta polypeptide displays 99% amino acid identity with the rat...
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