Article
Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes.
The EMBO journal - 1 Mar 1990
Grenningloh G, Schmieden V, Schofield P R, Seeburg P H, Siddique T, Mohandas T K, Becker C M, Betz H
Abstract excerpt
Two cDNAs encoding variants (alpha 1 and alpha 2) of the strychnine binding subunit of the inhibitory glycine receptor (GlyR) were isolated from a human fetal brain cDNA library. The predicted amino acid sequences exhibit approximately 99% and approximately 76% identity to the previously characte...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Southern
- Chromosome Mapping
- Cloning, Molecular
- DNA
- Gene Expression
- Genetic Variation
- Glycine
- Humans
- Hybrid Cells
- Macromolecular Substances
- Molecular Sequence Data