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Article

Demethylation-induced developmental pleiotropy in Arabidopsis.

Science (New York, N.Y.) - 2 Aug 1996

Ronemus M J, Galbiati M, Ticknor C, Chen J, Dellaporta S L

Abstract excerpt

The function of DNA methylation in higher plants was investigated by expression of a complementary DNA encoding a cytosine methyltransferase (MET1) from Arabidopsis thaliana as an antisense RNA in transgenic plants. This expression resulted in a 34 to 71 percent reduction in total genomic cytosine methylation. Loss of methylation was observed in both repetitive DNA and single-copy gene sequences. Developmental...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8662558
DOI: 10.1126/science.273.5275.654

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Demethylation-induced developmental pleiotropy in Arabidopsis.PMID 8662558Read ↗

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