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Article

Constitutive activation of STAT5 by the BCR-ABL oncogene in chronic myelogenous leukemia.

Oncogene - 18 Jul 1996

Shuai K, Halpern J, ten Hoeve J, Rao X, Sawyers C L

Abstract excerpt

Using chronic myelogenous leukemia (CML) as a model, we tested the hypothesis that cytokine-independent growth of leukemia cells results from aberrant activation of cytokine signaling pathways. The STAT5 (signal transducer and activator of transcription) protein, which is activated transiently in normal myeloid cells by cytokines such as GM-CSF (granulocyte-macrophage colony stimulating factor), was...

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Identifiers

PMID: 8710363

Genes

BCR
MOS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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