Article
C‐<i>myc</i> gene expression alone is sufficient to confer resistance to antiestrogen in human breast cancer cells
27 Mar 2002
Abstract excerpt
C-myc is implicated in the initiation, progression and estrogen response of breast cancer. To further investigate the role of c-myc in breast cancer, we have developed clonal MCF-7 human breast cancer cell lines harboring a stably-transfected human c-myc gene, whose expression was stringently controlled by the bacterial reverse tetracycline transcription activator protein. The expression of the endogenous genomic...
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