Article
The ancestral hemochromatosis haplotype is associated with a severe phenotype expression in Italian patients.
Hepatology (Baltimore, Md.) - 1 Jul 1996
Piperno A, Arosio C, Fargion S, Roetto A, Nicoli C, Girelli D, Sbaiz L, Gasparini P, Boari G, Sampietro M, Camaschella C
Abstract excerpt
We evaluate the relation between genotype and phenotype in 47 Italian male patients with homozygous genetic hemochromatosis (GH). Phenotype evaluation was based on the ratio of amount of iron removed (IR) by phlebotomy and age (IR/age). Patients were divided in two classes of phenotype expression: class I included 26 patients with less severe iron overload (IR/age <0.33) and class II included 21 patients with a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.