Article
Heterogeneity of hemochromatosis in Italy.
Gastroenterology - 1 May 1998
Piperno A, Sampietro M, Pietrangelo A, Arosio C, Lupica L, Montosi G, Vergani A, Fraquelli M, Girelli D, Pasquero P, Roetto A, Gasparini P, Fargion S, Conte D, Camaschella C
Abstract excerpt
BACKGROUND & AIMS: Patients with hemochromatosis show variable phenotype expression. We evaluated the frequency of hemochromatosis gene (HFE) mutations and the contribution of HFE genotype, ancestral haplotype, ethnic background, and additional factors (alcohol intake, hepatitis viruses, and beta...
Topics
- Adult
- Aged
- Female
- Gene Frequency
- Genetic Variation
- Genotype
- Haplotypes
- Hemochromatosis
- Humans
- Italy
- Male
- Middle Aged
- Mutation
- Phenotype