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Article

Polymorphism of glycogen synthetase gene in polycystic ovary syndrome.

Clinical endocrinology - 1 Jan 1996

Rajkhowa M, Talbot J A, Jones P W, Clayton R N

Abstract excerpt

OBJECTIVE: Polycystic ovary syndrome is a heterogeneous disorder associated with a moderate degree of insulin resistance and a higher risk of developing NIDDM. The exact mechanism of insulin resistance is unclear. This study examines the frequency of an Xbal polymorphism of the glycogen synthetase gene (A2 allele) as a marker of insulin resistance and seeks to relate the presence of the A2 allele to indices of...

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Identifiers

PMID: 8706299
DOI: 10.1046/j.1365-2265.1996.658474.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Polymorphism of glycogen synthetase gene in polycystic ovary syndrome.PMID 8706299Read ↗

Association between polymorphism of the glycogen synthase gene and non-insulin-dependent diabetes mellitus.Semantic proximity Read ↗

Association of Gly972Arg variant of insulin receptor substrate-1 with metabolic features in women with polycystic ovary syndrome.Semantic proximity Read ↗

Genetic determinants of insulin action in polycystic ovary syndrome.Semantic proximity Read ↗

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Study of association of IRS-1 and IRS-2 genes polymorphisms with clinical and metabolic features in women with polycystic ovary syndrome. Is there an impact?Semantic proximity Read ↗

Role of allelic variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in moderate-to-severe insulin resistance of women with polycystic ovary syndrome.Semantic proximity Read ↗

The G972R variant of the insulin receptor substrate-1 (IRS-1) gene is associated with insulin resistance in "uncomplicated" obese subjects evaluated by hyperinsulinemic-euglycemic clamp.Semantic proximity Read ↗

Polymorphism of the glycogen synthase gene in hypertensive and normotensive subjects.Semantic proximity Read ↗

Polymorphisms in the insulin receptor substrate-1 (IRS-1) gene and the insulin receptor substrate-2 (IRS-2) gene influence glucose homeostasis and body mass index in women with polycystic ovary syndrome and non-hyperandrogenic controlsSemantic proximity Read ↗

Glycogen synthase polymorphism, insulin resistance and hypertension.Semantic proximity Read ↗

Polymorphisms in the adiponutrin gene are associated with increased insulin secretion and obesity.Semantic proximity Read ↗

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