Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pasteurella haemolytica leukotoxin induces bovine leukocytes to undergo morphologic changes consistent with apoptosis in vitro.

Infection and immunity - 1 Jul 1996

Stevens P K, Czuprynski C J

Abstract excerpt

Infection of the bovine lung with Pasteurella haemolytica results in an acute respiratory disorder known as pneumonic pasteurellosis. One of the key virulence determinants used by this bacterium is secretion of an exotoxin that is specific for ruminant leukocytes (leukotoxin). At low concentrations, the leukotoxin can activate ruminant leukocytes, whereas at higher concentrations, it inhibits leukocyte functions...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal
Share to Apoptosis
Share to Cattle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Membrane

Share to Cell Nucleus

Share to In Vitro Techniques

Share to Leukocytes

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 8698496
DOI: 10.1128/iai.64.7.2687-2694.1996
PMCID: PMC174127

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pasteurella haemolytica leukotoxin induces bovine leukocytes to undergo morphologic changes consistent with apoptosis in vitro.PMID 8698496Read ↗

Prior exposure to Mannheimia haemolytica leukotoxin or LPS enhances beta(2)-integrin expression by bovine neutrophils and augments LKT cytotoxicity.Semantic proximity Read ↗

BHV-1 infection and inflammatory cytokines amplify the interaction of Mannheimia haemolytica leukotoxin with bovine peripheral blood mononuclear cells in vitroSemantic proximity Read ↗

Matrine and baicalin inhibit apoptosis induced by Panton-Valentine leukocidin of Staphylococcus aureus in bovine mammary epithelial cells.Semantic proximity Read ↗

Neutrophils are resistant to Yersinia YopJ/P-induced apoptosis and are protected from ROS-mediated cell death by the type III secretion system.Semantic proximity Read ↗

Cytotoxic activity of Mannheimia haemolytica strains in relation to diversity of the leukotoxin structural gene lktA.Semantic proximity Read ↗

A bovine CD18 signal peptide variant with increased binding activity to Mannheimia hemolytica leukotoxinSemantic proximity Read ↗

Inactivation of Pasteurella (Mannheimia) haemolytica leukotoxin causes partial attenuation of virulence in a calf challenge model.Semantic proximity Read ↗

Cloning, Sequencing, and Expression of the Leukotoxin Gene from<i>Fusobacterium necrophorum</i>Semantic proximity Read ↗

Leukotoxin operon and differential expressions of the leukotoxin gene in bovine Fusobacterium necrophorum subspeciesSemantic proximity Read ↗

Cytokine-mediated Bax deficiency and consequent delayed neutrophil apoptosis: A general mechanism to accumulate effector cells in inflammationSemantic proximity Read ↗

Leukotoxin fromAggregatibacter actinomycetemcomitanscauses shrinkage and P2X receptor-dependent lysis of human erythrocytesSemantic proximity Read ↗

Enhancement of apoptosis via an extrinsic factor, TNF-α, in cells infected with cytopathic bovine viral diarrhea virusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.