Article
Kinetics of removal and reappearance of non-transferrin-bound plasma iron with deferoxamine therapy.
Blood - 15 Jul 1996
Porter J B, Abeysinghe R D, Marshall L, Hider R C, Singh S
Abstract excerpt
The rapidity and duration of the response of non-transferrin-bound iron (NTBPI) to chelation therapy are largely unknown and have important implications for the design of optimal chelation regimens. Methodology was developed to measure simultaneously NTBPI, deferoxamine (DFO), and its major metabolite. NTBPI was present in all but 2 of 28 thalassaemia major (TM) patients who had received conventional subcutaneous...
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