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Article

A mechanism for reducing entropic cost of induced fit in protein--RNA recognition.

Biochemistry - 25 Jun 1996

Ribas de Pouplana L, Auld D S, Kim S, Schimmel P

Abstract excerpt

Induced fit has been postulated to be an important component of ligand interactions with proteins, including protein-DNA interactions. We imagined that the entropic cost of induced fit might be highly dependent on the local protein sequence context around critical contact residues. To investigate this question, we analyzed the basis for active or inactive phenotypes found in a library of combinatorial sequence...

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PMID: 8679560
DOI: 10.1021/bi960256a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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