Detection of aneuploidy in human and rodent sperm using FISH and applications of sperm assays of genetic damage in heritable risk evaluation.

doi:10.1016/0027-5107(95)00249-9

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Article

Detection of aneuploidy in human and rodent sperm using FISH and applications of sperm assays of genetic damage in heritable risk evaluation.

Mutation research - 10 Jun 1996

Wyrobek A J, Adler I D

Abstract excerpt

Efficient molecular methods are being developed for detecting various types of cytogenetic genetic damage in sperm, especially numerical aneuploidy for chromosomes involved in trisomies that survive at birth. These methods provide new approaches for identifying potentially detrimental environment...

Topics

Aneuploidy
Animals
Humans
In Situ Hybridization, Fluorescence
Male
Mice
Micronuclei, Chromosome-Defective
Mutagenicity Tests
Mutation
Risk Assessment
Rodentia
Spermatozoa

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