Stable variants of sperm aneuploidy among healthy men show associations between germinal and somatic aneuploidy.

doi:10.1086/340791

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Article

Stable variants of sperm aneuploidy among healthy men show associations between germinal and somatic aneuploidy.

American journal of human genetics - 1 Jun 2002

Rubes Jiri, Vozdova Miluse, Robbins Wendie A, Rezacova Olga, Perreault Sally D, Wyrobek Andrew J

Abstract excerpt

Repeated semen specimens from healthy men were analyzed by sperm fluorescence in situ hybridization (FISH), to identify men who consistently produced elevated frequencies of aneuploid sperm and to determine whether men who were identified as stable variants of sperm aneuploidy also exhibited higher frequencies of aneuploidy in their peripheral blood lymphocytes. Seven semen specimens were provided by each of 15...

Topics

Adult
Aneuploidy
Cell Size
Chromosomes, Human, Pair 8
Diploidy
Genetic Variation
Health
Humans
In Situ Hybridization, Fluorescence
Lymphocytes
Male
Sex Chromosomes
Sperm Count
Sperm Motility
Spermatozoa

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Identifiers

PMID: 11992257
DOI: 10.1086/340791
PMCID: PMC379139

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