Simultaneous detection of structural and numerical chromosome abnormalities in sperm of healthy men by multicolor fluorescence in situ hybridization.

doi:10.1007/s004390050268

Back to search

Article

Simultaneous detection of structural and numerical chromosome abnormalities in sperm of healthy men by multicolor fluorescence in situ hybridization.

Human genetics - 1 Nov 1996

Van Hummelen P, Lowe X R, Wyrobek A J

Abstract excerpt

Both structural and numerical chromosome aberrations in sperm represent important categories of paternally transmitted genetic damage. Therefore, a new multiprobe fluorescence in situ hybridization (FISH) method, using DNA probes for three targets (centromere and telomere of chromosome 1, centrom...

Topics

Adult
Animals
Chromosome Aberrations
Chromosomes, Human, Pair 1
Chromosomes, Human, Pair 8
Cricetinae
Humans
In Situ Hybridization, Fluorescence
Male
Middle Aged
Phenotype
Spermatozoa

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.