Article
Epigenetic modifications during oocyte growth correlates with extended parthenogenetic development in the mouse.
Nature genetics - 1 May 1996
Kono T, Obata Y, Yoshimzu T, Nakahara T, Carroll J
Abstract excerpt
In mammals, the maternal and paternal genomes are required for embryonic development. This is due to genomic imprinting which leads to the expression or repression of genes solely on the basis of the parent from which they were inherited. As a result, parthenogenetic embryos die before day 10 of gestation and show limited development of extra-embryonic membranes. Maternal imprinting is established during...
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