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Article

Mutational analysis of the carboxy-terminal region of UDP-glucuronosyltransferase 2B1.

DNA and cell biology - 1 Jun 1996

Meech R, Yogalingam G, Mackenzie P I

Abstract excerpt

UDP-glucuronosyltransferases (UGTs) are membrane-bound glycoproteins that are resident in the endoplasmic reticulum with a type I topology. The roles of the membrane-spanning and membrane-proximal cytoplasmic domains in UGT activity were investigated. Site-directed and deletional mutagenesis techniques were used to generate truncated forms of the enzyme, forms with altered residues, or forms with heterologous...

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Identifiers

PMID: 8672245
DOI: 10.1089/dna.1996.15.489

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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