Article
Selective recognition of malaria antigens by human serum antibodies is not genetically determined but demonstrates some features of clonal imprinting
1 Jan 1996
Abstract excerpt
Malaria infection induces the production of serum antibodies to a variety of malaria antigens but the prevalence of antibodies to any particular antigen is typically much less than 100%. It has been assumed that non-responsiveness to defined antigens in malaria immune subjects is due to HLS-mediated restriction of the immune response. In this study we have investigated the role of HLA and non-HLA genes in the...
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