Article
Allele-specific antibodies to Plasmodium falciparum merozoite surface protein-2 and protection against clinical malaria.
Parasite immunology - 1 Mar 2010
Osier F H A, Murungi L M, Fegan G, Tuju J, Tetteh K K, Bull P C, Conway D J, Marsh K
Abstract excerpt
IgG and IgG3 antibodies to merozoite surface protein-2 (MSP-2) of Plasmodium falciparum have been associated with protection from clinical malaria in independent studies. We determined whether this protection was allele-specific by testing whether children who developed clinical malaria lacked IgG/IgG3 antibodies specific to the dominant msp2 parasite genotypes detected during clinical episodes. We analysed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
