Article
New alleles of IGKV genes A2 and A18 suggest significant human IGKV locus polymorphism.
Immunogenetics - 1 Jan 1996
Atkinson M J, Cowan M J, Feeney A J
Abstract excerpt
The human kappa light chain consists of approximately 35 potentially functional IGKV genes. However, an estimation of the diversity in the IGKV repertoire of an individual will be affected by the extent of polymorphisms for the different IGKV genes and their patterns of inheritance. To date, little information is available to indicate the extent of allelic variation of the IGKV genes. We examined the extent of...
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