Article
Syncytia formation induced by coronavirus infection is associated with fragmentation and rearrangement of the Golgi apparatus.
Virology - 15 Jul 1996
Lavi E, Wang Q, Weiss S R, Gonatas N K
Abstract excerpt
Coronavirus mouse hepatitis virus (MHV) possesses a membrane glycoprotein (M) which is targeted to the Golgi apparatus (GA). We used immunocytochemistry with an organelle-specific antiserum to investigate the morphologic changes of the GA during infection of L2 murine fibroblasts with MHV-A59. Twenty-four hours after infection the GA was fragmented and translocated in the center of syncytia, while the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
