Article
Pantropic retroviral vectors integrate and express in cells of the malaria mosquito, Anopheles gambiae.
Proceedings of the National Academy of Sciences of the United States of America - 11 Jun 1996
Matsubara T, Beeman R W, Shike H, Besansky N J, Mukabayire O, Higgs S, James A A, Burns J C
Abstract excerpt
The lack of efficient mechanisms for stable genetic transformation of medically important insects, such as anopheline mosquitoes, is the single most important impediment to progress in identifying novel control strategies. Currently available techniques for foreign gene expression in insect cells in culture lack the benefit of stable inheritance conferred by integration. To overcome this problem, a new class of...
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