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Article

T cell receptor biases and clonal proliferations among lung transplant recipients with obliterative bronchiolitis.

The Journal of clinical investigation - 1 Jun 1996

Duncan S R, Valentine V, Roglic M, Elias D J, Pekny K W, Theodore J, Kono D H, Theofilopoulos A N

Abstract excerpt

Obliterative bronchiolitis (OB) is the most serious late complication of lung transplantation, but the pathogenesis of this disorder has not been elucidated. We sought evidence that OB is mediated by a cellular immunologic response by characterizing T cell antigen receptor beta-chain variable gene (TCRBV) repertoires in lung allograft recipients. Expression levels of 27 TCRBV among recipients were determined by...

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Identifiers

PMID: 8647959
DOI: 10.1172/JCI118714
PMCID: PMC507352

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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