Article
T regulatory cells in stable posttransplant bronchiolitis obliterans syndrome.
Transplantation - 15 Oct 2007
Mamessier Emilie, Lorec Anne-Marie, Thomas Pascal, Badier Monique, Magnan Antoine, Reynaud-Gaubert Martine
Abstract excerpt
BACKGROUND: Obliterative bronchiolitis (OB), mainly mediated by T cells, remains the major cause of morbidity and death in long-term lung transplant. Acute rejection (AR), also a T-cell mediated process, is strongly linked to OB. For unknown reasons, several patients with OB halt their pulmonary function decline and stabilize their obstructive defect for a long period. Our aim was to assess the T-cell activation...
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