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Article

Human rotavirus VP4 contains strain-specific, serotype-specific and cross-reactive neutralization sites.

Archives of virology - 1 Jan 1996

Kirkwood C D, Bishop R F, Coulson B S

Abstract excerpt

The neutralization epitopes of human rotavirus VP4 were studied by using a panel of neutralization monoclonal antibodies previously shown to be strain-specific (RV-3:3), serotype-specific (RV-5:2, ST-3:3) or cross-reactive (F45:4). Antigenic variants of human rotaviruses RV-3, ST-3, RV-5 and F45...

Topics

Amino Acid Sequence
Antibodies, Monoclonal
Antibodies, Viral
Antigens, Viral
Base Sequence
Capsid
Capsid Proteins
Cell Line
Cross Reactions
Epitope Mapping
Genetic Variation
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Neutralization Tests

Polymorphism, Single-Stranded Conformational

Rotavirus

Serotyping

Source

Identifiers

PMID: 8645097
DOI: 10.1007/BF01718319

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8645097-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Human rotavirus VP4 contains strain-specific, serotype-specific and cross-reactive neutralization sites.PMID 8645097Read ↗

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