Article
Evaluation of the mutagenicity of 'pan masala', a chewing substitute widely used in India.
Mutation research - 1 Aug 1990
Bagwe A N, Ganu U K, Gokhale S V, Bhisey R A
Abstract excerpt
Mutagenicity of polar and non-polar extracts of a popular brand of 'pan masala' was examined using the Salmonella/mammalian microsome test (Ames assay) and 2 tester strains of Salmonella typhimurium, TA98 and TA100. These extracts were also subjected to pretreatment with sodium nitrite at acidic pH, to simulate conditions for endogenous nitrosation. The aqueous, aqueous:ethanolic and chloroform extracts as well...
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