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Article

Vpr-induced cell cycle arrest is conserved among primate lentiviruses.

Journal of virology - 1 Apr 1996

Planelles V, Jowett J B, Li Q X, Xie Y, Hahn B, Chen I S

Abstract excerpt

We previously reported that expression of human immunodeficiency virus type 1 strain NL4-3 (HIV-1(NL4-3))vpr causes cells to arrest in the G2 phase of the cell cycle. We examined the induction of cell cycle arrest by other HIV-1 isolates and by primary lentiviruses other than HIV-1. We demonstrate that the vpr genes from tissue culture-adapted or primary isolates of HIV-1 are capable of inducing G2 arrest. In...

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Identifiers

PMID: 8642681
DOI: 10.1128/JVI.70.4.2516-2524.1996
PMCID: PMC190097

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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