Article
Role of the ceramide-signaling pathway in cytokine responses to P-fimbriated Escherichia coli.
The Journal of experimental medicine - 1 Mar 1996
Hedlund M, Svensson M, Nilsson A, Duan R D, Svanborg C
Abstract excerpt
Escherichia coli express fimbriae-associated adhesins through which they attach to mucosal cells and activate a cytokine response. The receptors for E. coli P fimbriae are the globoseries of glycosphingolipids; Gal alpha 1-->4Gal beta-containing oligosaccharides bound to ceramide in the outer lea...
Topics
- Animals
- Bacterial Adhesion
- Carbohydrate Conformation
- Carbohydrate Sequence
- Cell Line
- Ceramides
- Cytokines
- Enzyme Inhibitors
- Epithelium
- Escherichia coli
- Fimbriae, Bacterial
- Genotype
- Glycosphingolipids
- Guinea Pigs
- Hemagglutination
- Humans
- Interleukin-6
- Kidney Neoplasms